Mendeley
TY  _  JOUR
ID  -  2022120340308
TI  -  Effect of 8-week metabolic resistance training and Chlorogenic acid supplement on the expression of UCP1: A randomized clinical trial
JO  -  Journal of Sports Physiology and Athletic Conditioning
JA  -  ES
LA  -  en
SN  -  2783-3038
AU  -   تختی مریم
AU  -  Ghazalian farshad
AU  -  Sohaily Shahram
AU  -  Ebrahim Khosro
AD  -  دانشجو دکترا
AD  -  نویسنده مقاله
AD  -  
AD  -  نویسنده مقاله
Y1  -  2023
PY  -  2023
VL  -  7
IS  -  3
SP  -  50
EP  -  62
KW  -  metabolic resistance training
KW  -   green coffee
KW  -   obese and overweight women
KW  -   Uncoupling Protein 1. 
DO  -  
N2  -  Background: Obesity and overweight is one of the major public health challenges all around the world. The aim of this study was to evaluate the simultaneous effect of eight weeks of metabolic resistance training (MRT) and Chlorogenic Acid (CGA) supplementation on weight loss, expression level of UCP1in overweight women.
Materials and Methods: The present study was a randomized clinical trial performed in 2022 on a sample of overweight women in Iran. Participants in the study were randomly divided into four groups including combined 8-week course of MRT training and CGA supplementation, 8-week course of MRT, CGA supplement, and the control group. Intervention included three training sessions per week and the duration of each session was 45 minutes. The supplementation arms were also received 400 mg / day CGA extracted from green coffee beans. Expression level of Uncoupling Protein 1 (UCP1) was the main interested outcome that assessed pre and post intervention. 
Results: In the MRT exercise group, UCP1 expression increased by 4.3 units on average over the 8-week intervention. The highest increase was observed in participants who received both CGA supplement and MRT exercise where UCP1 increased from 22.5 (1.2) to 28.0 (3.5) over the study period (P<0.05). No significant increase was observed in CGA supplementation group. 
Conclusion: MRT exercises with and without CGA supplementation stimulated expression level of UCP1 mRNA.

UR  - rimag.ir/fa/Article/40308
L1  - rimag.ir/fa/Article/Download/40308
ER  -  
